Spectroscopy of Biological Compounds with Inelastic Electron Tunneling

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Science  28 Jun 1974:
Vol. 184, Issue 4144, pp. 1369-1371
DOI: 10.1126/science.184.4144.1369


Metal-insulator-metal electron tunnel junctions can be doped with a solution of an organic compound by placing a drop of the solution on the insulator and spinning of the excess. Electrical measurement of the second derivative of voltage with respect to current, as a function of applied voltage, then gives a spectrum of vibrational modes equivalent to an infrared or Raman spectrum, but with the use of only micrograms of sample.