Immediate Hypersensitivity Responses in Flatfish heat sensitive

See allHide authors and affiliations

Science  26 Jul 1974:
Vol. 185, Issue 4148, pp. 360-361
DOI: 10.1126/science.185.4148.360


Fungal extracts that precipitate with human C-reactive protein caused immediate erythema on subdermal injection into marine flatfish. Only species with calcium-dependent serum precipitins to these fungi showed skin reactions. Immediate hypersensitivity in a nonreactive species could be induced after injection with serum from reactive species. The transferable serum factor (or factors) was heat sensitive.