Transformation of Chick Embryo Neuroretinal Cells by Rous Sarcoma Virus in vitro: Induction of Cell Proliferation

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Science  23 Aug 1974:
Vol. 185, Issue 4152, pp. 709-710
DOI: 10.1126/science.185.4152.709


Neuroretinal cells from 7-day-old chick embryos are transformed and induced to proliferate after infection with Rous sarcoma virus in vitro. Susceptibility of neuroretinal cells to the virus is also dependent on the stage of development since infection of cells from 10-day-old embryos is uneffective.