Antibody to Leukemia Virus: Widespread Occurrence in Inbred Mice

Science  06 Sep 1974:
Vol. 185, Issue 4154, pp. 869-871
DOI: 10.1126/science.185.4154.869


Mice from a wide variety of inbred strains produce immunoglobulin G antibody against murine leukemia virus. This is contrary to the common view that the mouse is immunologically tolerant to its endogenous leukemia virus.