Isolated Brain Microvessels: A Purified, Metabolically Active Preparation from Bovine Cerebral Cortex

Science  13 Sep 1974:
Vol. 185, Issue 4155, pp. 953-955
DOI: 10.1126/science.185.4155.953


A purified, metabolically active preparation of brain microvessels was isolated from bovine cerebral cortex by using a simple procedure involving mild disruption of the tissue by homogenization and trapping of the vessels on nylon sieves. This preparation permits in vitro metabolic and structural studies of small blood vessels.