Normal Skin Test Responses in Chronic Marijuana Users

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Science  22 Nov 1974:
Vol. 186, Issue 4165, pp. 740-741
DOI: 10.1126/science.186.4165.740


The cell-mediated immunity of 22 chronic marijuana smokers showed no difference from that of normal controls when evaluated by in vivo skin testing with 2,4-dinitrochlorobenzene. However, a significant difference was seen between these chronic marijuana users, all of whom could be sensitized to 2,4-dinitro-chlorobenzene, and age-matched cancer patients, who showed a decreased capacity to be sensitized.