Reports

Mezerein: antileukemic principle isolated from Daphne mezereum L

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Science  21 Feb 1975:
Vol. 187, Issue 4177, pp. 652-653
DOI: 10.1126/science.1114315

Abstract

An alcohol-water extract of Daphne mezereum L., a plant widely used in folk medicine for treating cancers, showed antileukemic activity against the P-388 lymphocytic leukemia in mice. Systematic fractionation of the extract has led to isolation and characterization of mezerein as the principal antileukemic component.