Concanavalin A: its action in inducing Oocyte maturation-inducing substance in starfish follicle cells

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Science  21 Feb 1975:
Vol. 187, Issue 4177, pp. 654-655
DOI: 10.1126/science.1167977


Maturation of starfish oocytes is induced by 1-methyladenine produced in follicle cells under the influence of a gonad-stimulating hormonal peptide released from the nervous system. Concanavalin A stimulates isolated follicle cells to produce 1-methyladenine, which suggests that it has the same capacity as the peptide hormone to indirectly induce oocyte maturation.