Porphyrin triplet state probing the diffusion of oxygen in hemoglobin

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Science  07 Mar 1975:
Vol. 187, Issue 4179, pp. 836-838
DOI: 10.1126/science.1114327


Laser photolysis study of porphyrin-globin shows that the triplet state of the porphyrin is detectable by its light absorption and that it can be used to determine the rate of penetration of oxygen into the hemoglobin pocket in which the porphyrin is embedded. The oxygen penetration rate does not determine the binding rate of oxygen to iron in hemoglobin.