Reports

Yeast chromatin subunit structure

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Science  11 Apr 1975:
Vol. 188, Issue 4184, pp. 165-166
DOI: 10.1126/science.1090006

Abstract

Micrococcal nuclease digestion of in situ (intranuclear) and in vitro yeast chromatin produces distributions of DNA molecules of discrete sizes. In both cases, these molecules appear to be integral multiples of the smallest size on polyacrylamide gel electrophoresis. This result implies a widespread generic occurrence of the periodic organization of chromatin seen in mammalian systems.