Synaptic organization of the amine-containing interplexiform cells of the goldfish and Cebus monkey retinas

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Science  18 Apr 1975:
Vol. 188, Issue 4185, pp. 270-273
DOI: 10.1126/science.804181


Fluorescence microscopy has revealed a new type of amine-containing retinal neuron, the interplexiform cell, that extends processes in both plexiform layers. After intravitreal injection of 5,6-dihydroxytryptamine in goldfish and Cebus monkey, the processes of these cells can be identified by electron microscopy. In goldfish, the processes are pre- and postsynaptic to amacrine cells in the inner plexiform layer and presynaptic to bipolar and horizontal cells in the outer plexiform layer. Interplexiform cells thus provide an intraretinal centrifugal pathway from inner to outer plexiform layers.

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