Muscle activation: effects of small length changes on calcium release in single fibers

See allHide authors and affiliations

Science  12 Sep 1975:
Vol. 189, Issue 4206, pp. 881-884
DOI: 10.1126/science.1154025


In single muscle fibers, small (1 percent) changes of length have a marked effect of both the calcium activation and the tension elicited by a constant current stimulus. The decrease in tension with shortening is accounted for almost entirely by a decrease in calcium release, rather than by changes in mechanical factors, such as filament geometry.