Vasopressin: induced structural change in toad bladder luminal membrane

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Science  03 Oct 1975:
Vol. 190, Issue 4209, pp. 67-69
DOI: 10.1126/science.809840


Freeze-fracture electron microscopy demonstrates that vasopressin stimulation of isolated toad bladder alters the structure of the luminal membrane of granular cells. This alteration consists of an ordered aggression of intramembranous particles, and appears to be of functional significance, since the frequency of aggregation sites per area of membrane is closely correlated with vasopressin-induced osmotic water flow.