Direct observation of domains in wet lipid bilayers

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Science  24 Oct 1975:
Vol. 190, Issue 4212, pp. 383-384
DOI: 10.1126/science.1179216


Domain structure and phase separation in hydrated lipid bilayers have been imaged directly by selected reflection dark-field electron microscopy. Domains in multicomponent bilayers are much smaller than those in single component bilayers, in agreement with results obtained by selected area electron diffraction.