Tetrahymena: growth without phagocytosis

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Science  31 Oct 1975:
Vol. 190, Issue 4213, pp. 464-465
DOI: 10.1126/science.1166313


We have succeeded in growing a Tetrahymena mutant without food vacuoles in growth media supplemented with vitamins and heavy-metal salts. This finding implies the existence of adequate alternative routes of entry for every required nutrient, and clearly indicates that the food vacuole in Tetrahymena is a dispensable cellular organelle. The growth of the mutant without food vacuoles makes available a valuable experimental tool.