Delayed-type hypersensitivity to sheep red blood cells: inhibition of sensitization by interferon

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Science  07 Nov 1975:
Vol. 190, Issue 4214, pp. 574-576
DOI: 10.1126/science.1188355


Interferon, when given or induced 24 hours before contact of mice with sheep red blood cells, prevented sensitization, and no delayed-type hypersensitivity reaction could be elicited 4 days later, after challenge with the antigen, as shown by the absence of footpad swelling in treated animals.