Effects of long-term corn consumption on brain serotonin and the response to electric shock

Science  14 Nov 1975:
Vol. 190, Issue 4215, pp. 692-694
DOI: 10.1126/science.810890


Rats fed tryptophan-poor corn diets have reduced levels of brain serotonin and show increased responsiveness to electric shock. This diet-induced hyperalgesia can be reversed by feeding the animals diets with adequate amounts of tryptophan, or by systemic injections of the amino acid.