Retinal capillaries: proliferation of mural cells in vitro

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Science  05 Dec 1975:
Vol. 190, Issue 4218, pp. 985-986
DOI: 10.1126/science.810891


Capillaries from bovine, monkey, and human retinas maintained in tissue culture produced a monolayer of cells. Autoradiographic and electron microscopic evidence indicated that the mural cells (intramural pericytes) were the cells that proliferated. Since intramural pericytes are damaged selectively in diabetes mellitus, their availability in culture will be useful in seeking means to control diabetic retinopathy.