Formation of cyanamides from secondary amines in human saliva

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Science  19 Mar 1976:
Vol. 191, Issue 4232, pp. 1179-1180
DOI: 10.1126/science.942593


1-Morpholinocarbonitrile (1-cyanomorpholine) was formed from morpholine when this amine was incubated in whole human saliva. Several other secondary amines appeared to form analogous products, and this transformation may therefore represent a general metabolic pathway for amines in saliva.