Reports

Human Y-chromosome-specific reiterated DNA

Science  19 Mar 1976:
Vol. 191, Issue 4232, pp. 1189-1190
DOI: 10.1126/science.1257744

Abstract

Radiolabeled reiterated DNA specific for the human Y chromosome has been obtained by extensive reassociations between [3H]DNA prepared from men and excess DNA from women. These highly purifed labeled sequences reassociate only with DNA from individuals with a Y chromosome. The percentage of Y-chromosome-specific DNA isolated from individuals with differing numbers of Y chromosomes is a function of the number of chromosomes present. The purifed Y-chromosome-specific sequences may represent between 7 and 11 percent of the human Y chromosome.

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