Insulin-dependent diabetes: a disease of autoaggression

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Science  02 Apr 1976:
Vol. 192, Issue 4234, pp. 64-66
DOI: 10.1126/science.769160


Lymphocytes from patients with insulin-dependent diabetes demonstrated significant cytoadherence and cytotoxicity against human insulinoma cells in vitro as compared to lymphocytes from normals. Complement was not involved in insulinoma cell destruction. The findings suggest that insulin-dependent diabetes may be a disease of autoaggression.