Reports

Antiserum to somatostatin prevents stress-induced inhibition of growth hormone secretion in the rat

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Science  07 May 1976:
Vol. 192, Issue 4239, pp. 565-567
DOI: 10.1126/science.1257793

Abstract

Plasma growth hormone levels fall and remain low for several hours after stress in the rat. When antiserums to somatostatin are administered to rats prior to stress, growth hormone secretory pulses are partially restored. The results provide evidence that circulating somatostatin plays a prominent role in stress-induced inhibition of growth hormone secretion in the rat.