Aspartate: distinct receptors on Aplysia neurons

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Science  21 May 1976:
Vol. 192, Issue 4241, pp. 807-809
DOI: 10.1126/science.4895


Aplysia neurons have specific aspartate receptors that are distinct from those to glutamate. In some cells, asparate selectively increases the membrane permeability to chloride, giving rise to a hyperpolarization, while on other cells it increases the permeability to sodium, causing a depolarization. There are also specific receptors for L-glutamate which mediate sodium, chloride, or potassium conductance increases, and another class of receptors activated by both glutamate and aspartate.