Specificity of in vitro binding of primate Type C viral RNA and the homologous viral p12 core protein

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Science  23 Jul 1976:
Vol. 193, Issue 4250, pp. 326-328
DOI: 10.1126/science.180601


The binding of type C viral p12 proteins to purified viral RNA has been examined in vitro with the use of a family of closely related infectious primate type C viruses--the woolly monkey (SSAV) and gibbon (GALV) group. This in vitro protein-RNA binding is type specific. The system should serve as a model for studies of the evolution of nucleic acid binding proteins.