Dopaminergic agents: influence on serotonin in the molluscan nervous system

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Science  29 Oct 1976:
Vol. 194, Issue 4264, pp. 539-541
DOI: 10.1126/science.973139


Treatment of the mussel Mytilus edulis with 6-hydroxydopamine or with alpha-methyl-p-tyrosine decreased dopamine and increased serotonin in the nervous system. Treatment with dopamine decreased serotonin concentrations and prevented the effect of 6-hydroxydopamine. The serotonin concentration appears to be determined in part by the concentration of dopamine.