Photoreceptor mutant of Drosophia: is protein involved in intermediate steps of phototransduction?

Science  26 Nov 1976:
Vol. 194, Issue 4268, pp. 956-959
DOI: 10.1126/science.824732


In norpA mutants of Drosophila melanogaster the phototransduction process is either partially or completely blocked. By using a temperature-sensitive allele, we have found that that norpA mutation has little or no effect on either the rhodopsin-metarhodopsin transition or the machinery of quantum bump production. Thus, the norpA lesion appears to be localized in the intermediate process of phototransduction. Because a temperature-sensitive allele of norpA has been isolated, the norpA gene probably encodes a protein involved in the process.