Leucine 2,3-Aminomutase: A Cobalamin-Dependent Enzyme Present in Bean Seedlings

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Science  21 Jan 1977:
Vol. 195, Issue 4275, pp. 301-302
DOI: 10.1126/science.195.4275.301


Leucine 2,3-aminomutase has been demonstrated in extracts of bean seedlings. The activity of this enzyme is stimulated by coenzyme B12 and is inhibited by intrinsic factor. The inhibition is removed by the addition of coenzyme B12. This evidence is consistent with the presence of a cobalamin-dependent enzyme in higher Plants.