Reports

Lateral transport of a lipid probe and labeled proteins on a cell membrane

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Science  21 Jan 1977:
Vol. 195, Issue 4275, pp. 307-309
DOI: 10.1126/science.556653

Abstract

Diffusion coefficients (D) of a lipid probe and labeled proteins on L-6 myoblast membranes have been measured giving D(protein) approximately 2 X 10(-10) square centimeter per second and D (lipid probe) approximately 9 X 10(-9) square centimeter per second. Some of the membrane proteins are immobile, but the lipid probe diffuses freely over macroscopic distances. Cytochalasin B slows protein but not lipid probe diffusion.