Zinc binding: a difference between human and bovine milk

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Science  25 Feb 1977:
Vol. 195, Issue 4280, pp. 789-790
DOI: 10.1126/science.836589


Gel chromatography indicated that most of the zinc in cow's milk was associated with high-molecular-weight fractions, whereas zinc in human milk was associated with low-molecular-weight fractions. A species difference in zinc-binding ligands may explain why symptoms of the genetic disorder of zinc metabolism, acrodermatitis enteropathica, can be alleviated by feeding human but not cow's milk.