Membrane potential of mitochondrial measured with microelectrodes

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Science  04 Mar 1977:
Vol. 195, Issue 4281, pp. 898-900
DOI: 10.1126/science.841317


The membrane potentials of giant mitochondria from cuprizone-fed mice were found to be independent of metabolic state. Experiments are described in which the presence of the microelectrodes in the inner mitochondrial space, and the metabolic viability of the impaled mitochonidra, are validated.