H-Y antigen: behavior and function

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Science  11 Mar 1977:
Vol. 195, Issue 4282, pp. 956-960
DOI: 10.1126/science.320662


The factors are reviewed which affect the expression of H-Y antigen, a cell surface component that has been extensively analyzed in mice but which may be ubiquitous in all vertebrates. The phylogenetic stability of this antigen and its association with the Y chromosome indicate an important role in primary sex determination.