Stress-induced modulation of the immune response

See allHide authors and affiliations

Science  15 Apr 1977:
Vol. 196, Issue 4287, pp. 307-308
DOI: 10.1126/science.557841


After mice were exposed to a daily auditory stressor for varying lengths of time, the responses of their splenic lymphoid cells in vitro were assessed. Both the blastogenic activity of concanavalin A or lipopolysaccharide and the ability of immune lymphocytes to lyse P815 target cells showed the same patterns of immunosuppression and enhancement.