The cell membrane sodium pump as a mechanism for increasing thermogenesis during cold acclimation in rats

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Science  20 May 1977:
Vol. 196, Issue 4292, pp. 908-910
DOI: 10.1126/science.860125


Increased sodium pump activity is a major component of enhanced tissue thermogenesis in skeletal muscle, liver, and kidney of cold-acclimated rats. The sodium pump may play a major role in the thermoregulatory heat production during cold adaptation in mammals.