Cerebrospinal fluid production: stimulation by cholera toxin

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Science  27 May 1977:
Vol. 196, Issue 4293, pp. 1012-1013
DOI: 10.1126/science.193189


Large increases in the production of cerebrospinal fluid have been observed after the intraventricular administration of cholera toxin. Because cholera toxin stimulates adenylate cyclase, the data suggest that adenosine 3',5'-monophosphate plays a role in cerebrospinal fluid production.