Growth hormone: species-specific stimulation of erythropoiesis in vitro

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Science  03 Jun 1977:
Vol. 196, Issue 4294, pp. 1112-1113
DOI: 10.1126/science.870971


The effects of purifed bovine and human growth hormone were tested in vitro with murine and human bone marrow by means of granulocyte-monocyte and erythroid progenitor cloning techniques. Nanogram concentrations of the growth hormones potentiated erythropoietin-stimulated erythropoiesis, but not granulopoiesis, in a species-specific manner.