Antibody-induced antigen redistribution and shedding from human breast cancer cells

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Science  22 Jul 1977:
Vol. 197, Issue 4301, pp. 366-367
DOI: 10.1126/science.877557


Cell surface antigens of human breast cancer cells undergo a rapid redistribution when bound by antibodies from cancer patients. The subsequent shedding of these antigen-antibody complexes and free antigen may be instrumental in tumor survival.