Adipose tissue regeneration following lipectomy

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Science  22 Jul 1977:
Vol. 197, Issue 4301, pp. 391-393
DOI: 10.1126/science.877563


Surgical removal of subcutaneous fat depots in weanling rats leads to a regenerative response. If the rats are fed a diet high in fat, adipose mass and adipocyte number are precisely restored within 7 months of surgery. Thus, under appropriate experimental circumstances, compensatory hyperplasia will occur in adipose tissues of the rat.