Reports

Primary bioassay of human tumor stem cells

Science  29 Jul 1977:
Vol. 197, Issue 4302, pp. 461-463
DOI: 10.1126/science.560061

Abstract

A simple method has been developed to support human tumor stem cell colony growth in soft agar. The technique appears suitable for culture of a variety of neoplasms of differing histopathology. Tumor stem cell colonies arising from different types of cancer have differing growth characteristics and colony morphology. This bioassay should be suitable for clinical studies of effects of anticancer drugs or irradiation on human tumor stem cells.

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