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Temporal control of urate oxidase activity in Drosophila: evidence of an autonomous timer in malpighian tubules

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Science  29 Jul 1977:
Vol. 197, Issue 4302, pp. 477-479
DOI: 10.1126/science.406675

Abstract

The appearance of urate oxidase activity in the Malpighian tubules of Drosophlia melanogaster is synchronized with the time of emergence of the imago from the puparium. A developmental clock within the Malpighian tubules specifies the time of appearances of urate oxidase activity.