Polarity reversal in nerve-free hydra

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Science  19 Aug 1977:
Vol. 197, Issue 4305, pp. 771-773
DOI: 10.1126/science.887920


Hydra experimentally depleted of all nerve cells and nerve stem cells (interstitial cells) demonstrate normal polarity reversal. Thus hydra epithelial cells are capable of controlling complex developmental patterning phenomena.