Liquid chromatographic analysis of endogenous catecholamine release from brain slices

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Science  26 Aug 1977:
Vol. 197, Issue 4306, pp. 904-906
DOI: 10.1126/science.887928


A simple new liquid chromatographic technique has been applied to transmitter release studies in brain slice preparations. This method, which gives direct readings of picomoles of endogenous transmitter released, has been shown to yield reliable results with a variety of brain slice manipulations.