Induction of suppressor T cells in systemic lupus erythematosus by thymosin and cultured thymic epithelium

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Science  02 Sep 1977:
Vol. 197, Issue 4307, pp. 999-1001
DOI: 10.1126/science.302032


Patients with systemic lupus erythematosus lacked suppressor T cell function. Suppressor cell activity was induced in cells from many of these patients by incubation with thymosin or cultured thymic epithelium. These results suggest that thymic manipulation may be a useful therapeutic modality in this disease.