Estrogen formation in the early rabbit embryo

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Science  13 Jan 1978:
Vol. 199, Issue 4325, pp. 200-201
DOI: 10.1126/science.579477


Androgen formation (3beta-hydroxysteroid dehydrogenase activity) was detectable in the rabbit blastocyst on day 5 of gestation (before implantation); estrogen formation was first detectable on day 7. The capacity to form estrogen on the day of implantation suggests that estrogen formation in the blastocyst may play a role in the implantation process.