Double-stranded RNA is present in extracts of tobacco plants infected with tobacco mosaic virus

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Science  03 Feb 1978:
Vol. 199, Issue 4328, pp. 538-539
DOI: 10.1126/science.622553


Serologically specific electron microscopy was used to detect double-stranded RNA in extracts of tobacco infected with tobacco mosaic virus. Assays were made immediately after extraction, without purification, concentration, or treatment with phenol or detergent. This indicates that the double-stranded RNA is native and is not an artifact induced by purification methods.