Muscle crossbridge stroke and activity revealed by optical diffraction

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Science  17 Mar 1978:
Vol. 199, Issue 4334, pp. 1212-1213
DOI: 10.1126/science.415364


Optical diffraction measurements during rapid releases of active toad muscle show that the sarcomeres contract within 1 millisecond by an amount up to but not greater than 12 nanometers. This crossbridges immediately start cycling to produce the normal contraction velocity in unloaded muscle.