Genetic mapping of xenotropic leukemia virus-inducing loci in two mouse strains

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Science  31 Mar 1978:
Vol. 199, Issue 4336, pp. 1448-1449
DOI: 10.1126/science.204014


In genetic studies of C57BL/10 and BALB/c mice, inducibility of xenotropic murine leukemia virus from tissue cultures by treatment with 5-iododeoxyuridine shows single gene segregation ratios. In both strains, the virus-inducing loci are on chromosome 1, linked to the Dip-1/isozyme locus, but the two may not be at allelic sites.