Immunoassay of androgen binding protein in blood: a new approach for study of the seminiferous tubule

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Science  07 Apr 1978:
Vol. 200, Issue 4337, pp. 65-66
DOI: 10.1126/science.635573


Androgen binding protein, a secretory product of seminiferous tubules, was isolated by means of affinity chromatography. A radioimmunoassay was developed and used to identify androgen binding protein in rat plasma. The ability to measure a testicular protein in blood provides a new method for investigation of seminiferous tubular physiology.