Rejection of male skin grafts by splenectomized female mice

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Science  21 Apr 1978:
Vol. 200, Issue 4339, pp. 320-321
DOI: 10.1126/science.345443


Female mice of the C3H strain normally do not reject skin grafts from males of the same strain; however, 40 percent of splenectomized C3H female mice completely rejected C3H male skin grafts applied 2 weeks later. All splenectomized females showed at least transitory signs of graft rejection.