Identification of a C-glucuronide of delta6- tetrahydrocannabinol as a mouse liver conjugate in vivo

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Science  23 Jun 1978:
Vol. 200, Issue 4348, pp. 1390-1392
DOI: 10.1126/science.663618


Delta 6-Tetrahydrocannabinol-C-4-glucuronide was found in the livers of mice that had been administered delta 6-tetrahydrocannabinol. Thus, C-glucuronidation of a compound that contains a free hydroxyl group has been demonstrated in vivo.