Genetic basis of XX male syndrome and XX true hermaphroditism: evidence in the dog

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Science  18 Aug 1978:
Vol. 201, Issue 4356, pp. 644-646
DOI: 10.1126/science.675252


Serological analysis of white blood cells from the members of a family of American cocker spaniels indicates that a form of abnormal sexual development, in which individuals with a female karyotype have testes or ovotestes, is caused by anomalous transmission of male-determining H-Y genes.